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    Cell domestication

    We have rich experience in cell domestication, and understand of various media on the market. We can carry out fast and efficient domestication of cells provided by customers, and optimize the culture process, etc. A number of cell lines have been successfully domesticated, such as: serum-free suspension Hela-F cell line, serum-free suspension 293-F cell line, serum-free adherent Vero cell line, etc., and the tertiary cell bank system has been established; The Hela-F cell bank and the 293-F cell bank have passed the verification of the National Institutes for Food and Drug Control.
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    Cell Banking

    We have our own 293 adherent cell bank and 293-F serum-free suspension cell bank, which are verified by the National Institutes for Food and Drug Control, that can be directly used by customers to quickly carry out pharmaceutical research experiments . We can establish cell bank that meets the requirements of GMP for customers in a B+A environment, and can contact the National Institutes for Food and Drug Controlor other third-party to verify ; we have successfully established a bank.
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    Virus seed bank establishment

    We complete the establishment of virus seed batch systems for many customers, which has been verified by the National Institutes for Food and Drug Control, and actively promote the progress of customers' pharmaceutical research.
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    Serum-free process development

    The serum-free medium is a chemically defined medium with clear components, no animal origin, and easy to control physiological environment, which is conducive to the development of downstream purification processes, and has obvious advantages in the operation of culturing suspension cells to prepare viruses. The serum-free medium is a chemically defined medium with clear components, no animal origin, and easy to control physiological environment, which is conducive to the development of downstream purification processes, and has obvious advantages in the operation of culturing suspension cells to prepare viruses. Serum-free process is the development trend of biopharmaceutical cell culture technology. The composition of serum-free medium is safe and controllable. The serum-free process improves product quality and shortens the production cycle.
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    Large-scale cultivation technology

    Our fixed bed bioreactor is equipped with 2L cell tank, 5L cell tank, 7.5L cell tank and 14L cell tank, mainly used for 293 cell adherent culture, amplifying adenovirus, vaccinia virus, etc.; Eppendorf/NBS bioreactor, Univercells bioreactor and domestic bioreactor are optional.
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    Purification technology

    Yuanxing Gene has a genetic recombinant virus purification platform, which can purify various types of viruses, including adenovirus, vaccinia virus, lentivirus, herpes virus, adeno-associated virus, Newcastle disease virus, etc. The purification scale is adapted to the virus culture scale, and the maximum purification of the harvest liquid from a 200L scale bioreactor can be completed, and a recombinant virus product with high viral activity, high purity and high concentration that meets the specification of drug quality standards can be obtained, which can be used for basic research and preclinical research and clinical studies.
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