Adeno-associated viruses, from the parvovirus family, are small viruses with a genome of single stranded DNA. These viruses can insert genetic material at a specific site on chromosome 19 with near 100% certainty. There are a few disadvantages to using AAV, including the small amount of DNA it can carry (low capacity) and the difficulty in producing it. This type of virus is being used, however, because it is non-pathogenic (most people carry this harmless virus). In contrast to adenoviruses, most people treated with AAV will not build an immune response to remove the virus and the cells that have been successfully treated with it.
We specialty provides the CDMO services of adeno-associated virus products, such as production, purification, quality inspection and packaging, and can provide you with high titer and purity recombinant adeno-associated virus products, that are produced under GMP conditions and used for basic research, preclinical and clinical research.
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